Systematic, small‐scale screening with <scp> <i>Arabidopsis</i> </scp> reveals herbicides synergies that extend to lettuce

BACKGROUND Combining herbicides into a mixture is common approach used to overcome the potential for herbicide resistance in weeds. Many mixtures can be antagonistic and they are rarely synergistic. Here, 24 commercial herbicides, each representing different mode of action were create matrix all 276 unique combinations search new synergies agar using Arabidopsis thaliana. RESULTS Herbicides at an appropriate sublethal dose such that any gave visible growth inhibition. We found five including three ones, namely mesotrione–norflurazon, mesotrione–clethodim clomazone–paraquat. All reproducible soil-grown conditions. Interestingly, included bleaching herbicide, suggesting synergy might class-specific phenomenon. also mesotrione–norflurazon synergistic against lettuce (Lactuca sativa), but not tef (Eragrostis tef). CONCLUSION Our study shows screening A. thaliana efficient finding rare synergies.